Research
 Informed consent for clinical trials in acute coronary syndromes and stroke following the European Clinical Trials Directive: investigators' experiences and attitudes Piotr Iwanowski, Andrzej Budaj, Anna Czlonkowska, Wojciech Wasek, Beata Kozlowska-Boszko, Urszula Oledzka, Wojciech Maselbas Trials 2008, 9:45 (21 July 2008) [Abstract] [Provisional PDF] [PubMed] [Related articles] Study protocol
 Rationale, Design and Methodology for a Prospective Randomized Study of graft patency in Off-pump and On-pump MultI-Vessel coronary artery bypasS Surgery (PROMISS) using multidetector computed tomography Miguel S Uva, Fernando Matias, Sara Cavaco, Manuel P Magalhaes Trials 2008, 9:44 (17 July 2008) [Abstract] [Provisional PDF] [PubMed] [Related articles] Study protocol
 The TEAM trial : Safety and efficacy of endovascular treatment of unruptured intracranial aneurysms in the prevention of aneurysmal hemorrhages: A randomized comparison with indefinite deferral of treatment in 2002 patients followed for 10 years Jean Raymond, Andrew J. Molyneux, Allan J. Fox, S. CLAIBORNE Johnston, Jean-Paul Collet, Isabelle Rouleau Trials 2008, 9:43 (16 July 2008) [Abstract] [Provisional PDF] [PubMed] [Related articles] Study protocol
 Design paper: The CapOpus trial: A randomized, parallel-group, observer-blinded clinical trial of specialized addiction treatment versus treatment as usual for young patients with cannabis abuse and psychosis Carsten Hjorthøj, Allan Fohlmann, Anne-Mette Larsen, Mette TR Madsen, Lone Vesterager, Christian Gluud, Mikkel C Arendt, Merete Nordentoft Trials 2008, 9:42 (11 July 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Study protocol
 Multicenter Double Blind Trial of Autologous Bone Marrow Mononuclear Cell Transplantation through Intracoronary Injection post Acute Myocardium Infarction a MiHeart/AMI Study Hans F.R. Dohmann, Suzana A. Silva, Andre L.S. Souza, Alcione M. S. Braga, Rodrigo V. C. Branco, Andrea F. Haddad, Monica A. Oliveira, Rodrigo C. Moreira, Fabio A. A. Tuche, Cintia M. Peixoto, Bernardo R. Tura, Radovan Borojevic, Jorge P. Ribeiro, Jose C. Nicolau, Antonio C. Nobrega, Antonio C. C. Carvalho Trials 2008, 9:41 (3 July 2008) [Abstract] [Provisional PDF] [PubMed] [Related articles] Research
 Clinical and cost-effectiveness analysis of an open label, single-centre, randomised trial of spinal cord stimulation (SCS) versus percutaneous myocardial laser revascularisation (PMR) in patients with refractory angina pectoris: The SPiRiT trial M T Dyer, KA Goldsmith, SN Khan, LD Sharples, C Freeman, I Hardy, MJ Buxton, PM Schofield Trials 2008, 9:40 (30 June 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Research
  Inefficacy of different strategies to improve guideline awareness 5-year follow-up of the hypertension evaluation project (HEP) Jens Hagemeister, Christian A Schneider, Holger Diedrichs, Diana Mebus, Holger Pfaff, Gernot Wassmer, Hans W Höpp Trials 2008, 9:39 (25 June 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Study protocol
 Effectiveness of the Austrian disease-management-programme for type 2 diabetes: study protocol of a cluster-randomized controlled trial Andreas C Sönnichsen, Andreas Rinnerberger, Maria G Url, Henrike Winkler, Peter Kowatsch, Gert Klima, Bernhard Fürthauer, Raimund Weitgasser Trials 2008, 9:38 (19 June 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Study protocol
  The third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke Peter Sandercock, Richard Lindley, Joanna Wardlaw, Martin Dennis, Steff Lewis, Graham Venables, Adam Kobayashi, Anna Czlonkowska, Eivind Berge, Karsten Bruins Slot, Veronica Murray, Andre Peeters, Graeme Hankey, Karl Matz, Michael Brainin, Stefano Ricci, Maria Grazia Celani, Enrico Righetti, Teresa Cantisani, Gord Gubitz, Steve Phillips, Antonio Arauz, Kameshwar Prasad, Manuel Correia, Phillippe Lyrer, the IST-3 collaborative group Trials 2008, 9:37 (17 June 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Study protocol
 Automated external cardioversion defibrillation monitoring in cardiac arrest: a randomized trial Bakhtiar Ali, Heather Bloom, Emir Veledar, Dorothy House, Robert Norvel, Samuel C Dudley, A Maziar Zafari Trials 2008, 9:36 (11 June 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Study protocol
 The SU.FOL.OM3 Study: a secondary prevention trial testing the impact of supplementation with folate and B-vitamins and/or Omega-3 PUFA on fatal and non fatal cardiovascular events, design, methods and participants characteristics Pilar Galan, Serge Briancon, Jacque Blacher, Sébastien Czernichow, Serge Hercberg Trials 2008, 9:35 (10 June 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Research
 Randomised, crossover clinical trial, in healthy volunteers, to compare the systemic availability of two topical intranasal budesonide formulations Jaime Algorta, Maria Angeles Pena, Silvia Francisco, Zurine Abajo, Emilio Sanz Trials 2008, 9:34 (9 June 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Study protocol
 Study protocol for a three-armed randomized controlled trial to assess whether house screening can reduce exposure to malaria vectors and reduce malaria transmission in The Gambia Matthew J Kirby, Paul J Milligan, David J Conway, Steve W Lindsay Trials 2008, 9:33 (6 June 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Study protocol
 Efficacy of tibolone and raloxifene for the maintenance of skeletal muscle strength, bone mineral density, balance, body composition, cognitive function, mood/depression, anxiety and quality of life/well-being in late postmenopausal women 70 years: Study design of a randomized, double-blind, double-dummy, placebo-controlled, single-center trial Didy E Jacobsen, Monique M Samson, Yvonne T van der Schouw, Diederick E Grobbee, Harald JJ Verhaar Trials 2008, 9:32 (5 June 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Commentary
  Do we want more cancer patients on clinical trials If so, what are the barriers to greater accrual Andrew J Vickers Trials 2008, 9:31 (3 June 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Commentary
 Competing risk and heterogeneity of treatment effect in clinical trials David M Kent, Alawi Alsheikh-Ali, Rodney A Hayward Trials 2008, 9:30 (22 May 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Study protocol
 GENetic and clinical Predictors Of treatment response in Depression: the GenPod randomised trial protocol Laura Thomas, Jean Mulligan, Victoria Mason, Debbie Tallon, Nicola Wiles, Philip Cowen, David Nutt, Michael O'Donovan, Deborah Sharp, Tim Peters, Glyn Lewis Trials 2008, 9:29 (22 May 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Study protocol
  GALA: an international multicentre randomised trial comparing general anaesthesia versus local anaesthesia for carotid surgery Michael J Gough, Andrew Bodenham, Michael Horrocks, Bridget Colam, Steff C Lewis, Peter M Rothwell, Adrian P Banning, David Torgerson, Moira Gough, Demosthenes Dellagrammaticas, Anne Leigh-Brown, Christos Liapis, Charles Warlow Trials 2008, 9:28 (21 May 2008) [Abstract] [Full Text] [PDF] [PubMed] [Related articles] Book review
 Review of: Interpreting and Reporting Clinical Trials A guide to the CONSORT statement and the principles of randomised controlled trials by Anthony Keech, Val Gebski and Rhana Pike Stephen JW Evans Trials 2008, 9:27 (19 May 2008) [Abstract] [Full Text] [PDF] Book review
 Review of "Evaluating Clinical Research All that glitters is not gold" by Bengt D. Furberg and Curt D. Furberg Desmond Julian Trials 2008, 9:26 (9 May 2008) [Abstract] [Full Text] [PDF]
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