|
Characteristics of included publications |
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| Author |
Year |
Sample Size (N completed) |
Treatment Comparison |
|
|
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| Topouzis et al [40] |
2007 |
332 |
Travoprost 0.004%/timolol 0.5% versus once-daily latanoprost 0.005%/timolol 0.5% |
| Hommer [43] |
2007 |
430 |
FC bimatoprost 0.03%/timolol 0.5% versus non-FC bimatoprost 0.03%/timolol 0.5% |
| Hollo et al [44] |
2006 |
192 |
Timolol maleate versus brinzolamide both added to travoprost |
| Brittain et al [20] |
2006 |
46 |
Combination timolol 0.5% and latanoprost 0.005% versus bimatoprost 0.03% |
| Day et al [21] |
2005 |
32 |
bimatoprost 0.03% versus timolol maleate 0.5%/dorzolamide 2% FC |
| Netland et al [45] |
2003 |
25 |
Brimonidine purite + bimatoprost versus timolol + latanoprost |
| Thomas et al [28] |
2003 |
26 |
Latanoprost versus brimonidine |
| Whitcup et al [16] |
2003 |
550 |
Bimatoprost versus timolol |
| Netland et al [23] |
2001 |
760 |
Travoprost versus latanoprost versus timolol |
| Larsson [24] |
2001 |
24 |
Latanoprost 0.005% versus timolol gel-forming solution 0.5% |
| Fechtner et al [42] |
2004 |
238 |
FC dorzolamide 2%/timolol 0.5% (COSOPT™) versus latanoprost 0.005% (XALATAN™) |
| Cohen et al [17] |
2004 |
284 |
Bimatoprost versus timolol |
| Shin et al [31] |
2004 |
242 |
FC latanoprost/timolol versus FC dorzolamide/timolol |
| Tomita et al [25] |
2004 |
39 |
Latanoprost versus timolol |
| Stewart et al [46] |
2004 |
32 |
Latanoprost/timolol maleate FC versus concomitant brimonidine and latanoprost therapy |
| Gandolfi et al [11] |
2001 |
214 |
Bimatoprost versus latanoprost |
| Watson et al [26] |
1996 |
268 |
Latanoprost versus timolol |
| Konstas et al [57] |
2002 |
35 |
Once-daily morning versus evening dosing of concomitant latanoprost/timolol |
| Day et al [47] |
2003 |
31 |
Timolol 0.5%/Dorzolamide 2% FC versus timolol maleate 0.5% and unoprostone... |
| Parrish et al [12] |
2003 |
410 |
Latanoprost versus bimatoprost versus Travoprost |
| Konstas et al [32] |
2004 |
32 |
FC latanoprost 0.005%/timolol maleate 0.5% versus FC dorzolamide 2%/timolol maleate 0.5% |
| Sharpe et al [48] |
2005 |
29 |
Brimonidine 0.2% versus unoprostone 0.15% both added to timolol maleate 0.5% |
| Higginbotham et al [18] |
2002 |
1009 |
Bimatoprost versus timolol |
| Pfeiffer [33] |
2002 |
396 |
FC latanoprost and timolol versus its individual components |
| Higginbotham et al [34] |
2002 |
345 |
FC latanoprost and timolol versus monotherapy with either components |
| Konstas et al [49] |
2008 |
53 |
Latanoprost and dorzolamide/timolol FC after 2 and 6 months of treatment |
| Konstas et al [37] |
2007 |
40 |
Latanoprost versus travoprost |
| Franks et al [39] |
2006 |
106 |
Travoprost 0.004% versus FC latanoprost 0.005%/timolol 0.5% |
| Diestelhorst et al [35] |
2006 |
502 |
FC latanoprost and timolol in the evening versus concomitant use of the individual components |
| Hughes et al [41] |
2005 |
293 |
FC travoprost 0.004%/timolol 0.5% ophthalmic solution versus concomitant use of the individual components |
| Schuman et al [50] |
2005 |
387 |
FC travoprost 0.004%/timolol 0.5% versus concomitant travoprost 0.004% + timolol 0.5 versus timolol BID control |
| Konstas et al [29] |
2005 |
31 |
Brimonidine purite versus dorzolamide each added to latanoprost |
| Diestelhorst et al [36] |
2004 |
190 |
FC latanoprost/timolol versus concomitant latanoprost and timolol |
| Coleman et al [22] |
2003 |
168 |
Bimatoprost (LUMIGAN) versus combined timolol and dorzolamide (COSOPT) |
| Zimmerman et al [13] |
2003 |
2775 |
Various POAG monotherapy versus latanoprost |
| Stewart et al [51] |
2003 |
29 |
FC timolol maleate/latanoprost versus timolol maleate + brimonidine |
| Noecker et al [14] |
2003 |
249 |
Bimatoprost versus latanoprost |
| Honrubia et al [52] |
2002 |
217 |
Latanoprost 0.005% versus FC dorzolamide 2% & timolol 0.5% |
| Simmons et al [30] |
2002 |
107 |
Brimonidine versus latanoprost in patients uncontrolled on β – blockers |
| Goldberg et al [38] |
2001 |
507 |
Topical travoprost versus timolol BID |
| DuBiner et al [15] |
2001 |
59 |
Bimatoprost versus latanoprost |
| Brandt et al [19] |
2001 |
556 |
QD, BID bimatoprost versus timolol BID |
| Susanna et al [53] |
2001 |
98 |
Latanoprost versus unoprostone |
| Diestelhorst et al [54] |
2000 |
179 |
Latanoprost versus pilocarpine T.I.D |
| Stewart et al [55] |
1999 |
30 |
Timolol solution versus timolol gel each added to latanoprost |
| Konstas et al [27] |
1999 |
34 |
Latanoprost versus timolol maleate |
| Petounis et al [56] |
2001 |
148 |
Latanoprost versus dorzolamide each added to timolol |
Eyawo et al. Trials 2008 9:69 doi:10.1186/1745-6215-9-69 |
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