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 Welcome to Trials

Do we want more cancer patients on clinical trials?

The key metric is not the number of patients on clinical trials, but the number on the sort of trials that can be used as a basis for clinical decisions, explains Trials Associate Editor, Andrew J Vickers in his latest commentary. Financial and regulatory barriers to greater clinical participation are also discussed.

See related research article by Wright et al., http://www.trialsjournal.com/content/9/1/12


Research    
Informed consent for clinical trials in acute coronary syndromes and stroke following the European Clinical Trials Directive: investigators' experiences and attitudes
Piotr Iwanowski, Andrzej Budaj, Anna Czlonkowska, Wojciech Wasek, Beata Kozlowska-Boszko, Urszula Oledzka, Wojciech Maselbas
Trials 2008, 9:45 (21 July 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]




Study protocol    
Rationale, Design and Methodology for a Prospective Randomized Study of graft patency in Off-pump and On-pump MultI-Vessel coronary artery bypasS Surgery (PROMISS) using multidetector computed tomography
Miguel S Uva, Fernando Matias, Sara Cavaco, Manuel P Magalhaes
Trials 2008, 9:44 (17 July 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]




Study protocol    
The TEAM trial : Safety and efficacy of endovascular treatment of unruptured intracranial aneurysms in the prevention of aneurysmal hemorrhages: A randomized comparison with indefinite deferral of treatment in 2002 patients followed for 10 years
Jean Raymond, Andrew J. Molyneux, Allan J. Fox, S. CLAIBORNE Johnston, Jean-Paul Collet, Isabelle Rouleau
Trials 2008, 9:43 (16 July 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]




Study protocol    
Design paper: The CapOpus trial: A randomized, parallel-group, observer-blinded clinical trial of specialized addiction treatment versus treatment as usual for young patients with cannabis abuse and psychosis
Carsten Hjorthøj, Allan Fohlmann, Anne-Mette Larsen, Mette TR Madsen, Lone Vesterager, Christian Gluud, Mikkel C Arendt, Merete Nordentoft
Trials 2008, 9:42 (11 July 2008)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]




Study protocol    
Multicenter Double Blind Trial of Autologous Bone Marrow Mononuclear Cell Transplantation through Intracoronary Injection post Acute Myocardium Infarction a MiHeart/AMI Study
Hans F.R. Dohmann, Suzana A. Silva, Andre L.S. Souza, Alcione M. S. Braga, Rodrigo V. C. Branco, Andrea F. Haddad, Monica A. Oliveira, Rodrigo C. Moreira, Fabio A. A. Tuche, Cintia M. Peixoto, Bernardo R. Tura, Radovan Borojevic, Jorge P. Ribeiro, Jose C. Nicolau, Antonio C. Nobrega, Antonio C. C. Carvalho
Trials 2008, 9:41 (3 July 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]






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 ISSN: 1745-6215

Trials was formerly published as Current Controlled Trials in Cardiovascular Medicine [more info].



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